Preheat the oven to 400 degrees. Line a large baking sheet with parchment paper or foil.
To prepare the meatballs, in a large bowl, combine the panko breadcrumbs and milk and mix to combine. Let stand for 5 to 10 minutes.
Add the beef and pork to the breadcrumb-milk mixture, along with the parmesan cheese, onion, garlic, egg, fresh parsley/basil, Italian herbs, Worcestershire sauce, 1 teaspoon salt, and 1/4 teaspoon black pepper. Mix until just combined, being careful not to overmix.
Using a cookie scoop or your hands, gently shape the mixture into 20 to 24 meatballs, each using about 2-tablespoons of the meat mixture. If the meat is sticking to your hands, brush your hands with a little olive oil. Transfer the meatballs to the prepared pan.
Bake for 15 to 25 minutes (timing depends on the size of your meatballs), until an instant-read thermometer reads 160 degrees. If desired, brown the meatballs under the broiler for a minute or two. Transfer the baking pan to a wire rack to cool.
Meanwhile, to make the sauce, in a large saucepan, combine the crushed tomatoes, tomato paste, Italian seasoning, sugar (if using), 1 teaspoon salt, 1/4 teaspoon black pepper, and red pepper flakes. Set the pan over medium heat and bring to a simmer. Reduce the heat to medium-low, partially cover and simmer for 10 minutes.
When the meatballs have finished baking, add them to the sauce. Stir to coat and simmer for 2 to 3 minutes to heat through.
Spoon the meatballs and sauce over cooked pasta and top with fresh herbs. Serve with parmesan cheese on the side.